Endocardial Fibroelastosis

A condition characterized by the thickening of endocardium (the innermost layer of the heart, comprised of endothelial cells.) due to proliferation of fibrous and elastic tissue, usually in the left ventricle leading to impaired cardiac function. It is often associated with congenital heart anomalies, infection, or gene mutation. Affected animals are usually less than 6 months of age.

Signs of Endocardial Fibroelastosis

Affected dogs often have signs of left-sided heart failure. Breeds affected by this disease include Labrador Retrievers, Great Dane, English Bulldog, English Springer Spaniels and Boxer. Signs, treatment and outlook are similar to those for dilated cardiomyopathy (CDM).