Juvenile Cellulitis

Juvenile cellulitis, or puppy strangles, is an uncommon disease. The condition is presumed to be immune-mediated based on histopathologic features and response to immunosuppressive forms of therapy. A heritable nature has been suggested.

Dachshunds, Golden Retrievers, yellow Labrador Retrievers, Gordon setters, Lhasa Apsos, and Pointers are most commonly affected, but any other breed can have this disease. Most affected animals are less than 4 months old, but occasionally the disorder is reported in adults. Several puppies or only one in the litter may be affected. Signs are characterized by vesicles or pustules in the inner surface of the outer ear, on the muzzle, lips, and eyelids which rapidly progresses to extensive facial swelling, abscesses and draining lesions. Occasionally lymph nodes will abscess and drain. A few cases will develop nodules over the trunk, penis and anus areas due to a panniculitis. Puppies usually have fever, are depressed and lose appetite. Permanent areas of alopecia and scarring may result if the lesions are extensive.

Diagnosis Diagnosis is based on history, clinical signs, cytologic examination of draining inflammatory fluid, skin biopsy and response to therapy. Skin scrapings are performed to rule out demodicosis. Bacterial cultures sometimes reveal organisms, although they are secondary infection. Although juvenile cellulitis has many clinical similarities to pyoderma, it responds to corticosteroid therapy. Antibiotics are used to treat secondary infection.

Treatment Treatment with a bactericidal antibiotic (cephalexin, cephadroxil) and immunosuppressive doses of corticosteroids (prednisolone, 1.1 mg/kg twice a day) is required for 2 to 3 weeks. Once lesions have resolved reduce the dose slowly to an alternate day schedule to prevent relapses. The condition usually responds completely, with little chance of recurrence. Owners should be prepared for scarring which may be permanent.

Prognosis

References
1. Nesbitt G.E. & Ackerman L.J. Canine Immune-Mediated Skin Diseases. In: Canine and Feline Dermatology: Diagnosis and Treatment. Veterinary Learning Systems, Trenton, New Jersey

Go Pets America recommends seeking the advice of your local veterinarian for the most appropriate vaccination program and for the diagnosis and treatment of your pet's health problems. For vaccination requirements please contact your state and local licensing authorities.