Pug Dog Encephalitis (PDE)

Pug Dog Encephalitis is an inflammatory disease of the brain affecting Pug dogs of either sex. The disease used to be considered unique to the Pug breed. However, similar disease has benn reported recently in Maltese, Pekingese and Yorkshire Terrier breeds.

Pug dog encephalitis is one of the inflammatory diseases of the central nervous system (CNS) which cause seizures in dogs: canine distemper, rabies, toxoplasmosis, Rocky Mountain spotted fever and several other diseases. If a dog of less than 1 or greater than 5 years of age suffers persistent seizures, it should be thoroughly examined and tested for these neurological disorders.

Pug dog encephalitis can last from several days to 6 months or more and usually starts in its acute, rapidly progressing form. Symptoms include seizures, depression, abnormal gait, blindness, staring off into space, pressing head against the wall or furniture, ataxia (a staggering walk), and intermittent screaming. What causes this disease is still unknown. It is believed to be a genetic condition, as littermates and closely related dogs are often affected, but it also occurs in Pugs born from non-related lines. The disease has no cure.

Pug dog encephalitis is hard to diagnose since its symptoms often relate to other CNS diseases. Seizures may be caused by many other underlying conditions such as hypoglycemia, canine distemper, rabies, toad poisoning, chemicals and toxic plants ingestion.

Sometimes it is possible to make the correct diagnosis using the magnetic resonance imaging of the brain (MRI), or analyzing the white blood cells in the spinal fluid. But most often the disease is diagnosed after the dog dies.

Although PDE is always terminal, treatment may control seizures and reduce the inflammatory process in the brain for a short period of time.

Go Pets America recommends seeking the advice of your local veterinarian for the most appropriate vaccination program and for the diagnosis and treatment of your pet's health problems. For vaccination requirements please contact your state and local licensing authorities.