Renal Cystadenocarcinoma and Nodular Dermatofibrosis
The terms "carcinoma" and "adenocarcinoma" (AC) generally apply to cancers that arise in the epithelial tissues of skin and body organs. Carcinoma is often used synonymously with "cancer," because 80 to 90 percent of human cases of cancer are carcinomas. Adenocarcinomas originate in abnormal gland cells that are in the lining or inner surface of a cavity or organ. Adenomas are benign tumors of gland cells that, over time, may transition to malignant tumors. The skin and delicate mucous membranes are commonly affected in senior pets. Dogs are prone to develop sebaceous, apocrine (anal sac), perianal, ceruminous, salivary, and sweat gland tumors, while cats are prone to basal cell tumors. The biological behavior of most adenocarcinomas is aggressive with a persistent tendency for metastasis.
Both in animals and humans, kidney tumors may be caused by chemical substances, physical trauma, or viral infections. Chemical substances known to cause kidney cancers in animals are nitrosamines, aromatic amines (dyes, rubber, gas, coal), triphosphates, cadmium, aflatoxins, and lead.