Milbemycin Oxime
Milbemycin oxime (Interceptor® Interceptor® Interceptor® Flavor Tabs® SafeHeart™, Sentinel® Flavor Tabs® ) is approved by FDA for prevention of heartworm disease caused by Dirofilaria immitis, control of hookworm infections caused by Ancylostoma caninum, and removal and control of adult roundworm infections caused by Toxocara canis and Toxascaris leonina and whipworm infections caused by Trichuris vulpis in dogs and in puppies 4 weeks of age or greater and 2 pounds of body weight or greater. 2
Milbemycin oxime is approved by FDA for prevention of heartworm disease caused by Dirofilaria immitis and the removal of adult Toxocara cati (roundworm) and Ancylostoma tubaeforme (hookworm) infections in cats 6 weeks of age or greater and 1.5 pounds body weight or greater.2
Milbemycin oxime (Milbemite™ Otic Solution) is also approved by FDA for the treatment of ear mite (Otodectes cynotis) infestations in cats and kittens 4 weeks of age and older. 2
Milbemycin oxime (Sentinel® Flavor Tabs® and Capstar® Flea Management System™ ) is indicated for use in dogs and cats for the concurrent use of flavored milbemycin oxime and lufenuron tablets with nitenpyram tablets as in is indicated to kill adult fleas and prevent flea eggs from hatching.
Mild allergic reactions have been reported in dogs with a large number of circulating Dirofilaria microfilaria. High dosage in Collie dogs may cause incoordination, fever and reluctance to rise. 4
References:
REF FILE 324-DAC
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