Endocardial Fibroelastosis

Endocardial fibroelastosis is a type of heart disease characterized by the thickening of the endocardium due to proliferation of fibrous and elastic tissue. The disease has been reported in dogs and cats and is probably familial in some lines of Burmese and Siamese cats.1 Affected animals are usually less than six months of age.

There are several types of endocardial fibroelastosis. Primary endocardial fibroelastosis involves endocardial layer of the left ventricle without any associated congenital abnormality. Another type, designated as secondary endocardial fibroelastosis, often accompanies congenital heart anomalies, such as aortic stenosis, coarctation of the aorta, and abnormal origin of the left coronary artery from the pulmonary trunk.3,2 Affected dogs often have signs of left-sided or biventricular heart failure. Heart murmur may be present. Breeds affected by this disease include the Labrador Retriever, Great Dane, English Bulldog, English Springer Spaniel, and Boxer. Treatment and outlook are similar to those for dilated cardiomyopathy.


  1. Stephen J. Ettinger, DVM, DACVIM and Edward C. Feldman, DVM, DACVIM. Textbook of Veterinary Internal Medicine
  2. Joseph K. Perloff. The Clinical Recognition of Congenital Heart Disease
  3. Richard W. Nelson, C. Guillermo Couto. Small Animals Internal Medicine

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